Molecular group:
Immune cells
Molecule/Cell:
Platelets
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^7
Mouse genetic background (Con):
CBA/J
Experimental treatment group (EG):
anti-platelet
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (97%)
Pathology (EG):
CM (31,5%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
Anti-platelet (LFA-1+) antibodies prevented CM even when administered on day 6
Refs:
Grau et al., 1993, Eur Cytokine Netw
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