Molecular group:
Immune cells
Molecule/Cell:
Monocyte/Macrophages
Plasmodium strain:
Plasmodium chabaudi AS
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
Chemical depletion of macrophages (silica)
Lethal infection (Con):
no
Lethal infection (EG):
40-70%
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Delayed clearance (exp1); increased peak (exp2)
Additional phenotypes (EG vs Con):
N.I.
Refs:
Stevenson et al., 1989, Parasite Immunol
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