Molecular group:
Immune cells
Molecule/Cell:
Va14+ NKT cell
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^4
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
Backcrossed for 9 generations
Experimental treatment group (EG):
Ja281 -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
CM (100%)
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Delayed onset of disease symptoms (~ 2 days)
Refs:
Hansen et al., 2003, Immunity
Hyperlink: