Molecular group:
Immune cells
Molecule/Cell:
NKT cell
Plasmodium strain:
Plasmodium berghei K173
pRBC infection titer:
2 x 10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
CD1d -/-
Lethal infection (Con):
N.I.
Lethal infection (EG):
N.I.
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
Similar plasma IFN-g and splenic IFN-g mRNA expression 24h p.i.
Refs:
Mitchell et al., 2005, Infect Immun
Hyperlink: