Molecular group:
Immune cells
Molecule/Cell:
NK cells
Plasmodium strain:
Plasmodium berghei NK65
pRBC infection titer:
10^3 or 10^6 or 10^8
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
Beige mutation (bg/ bg) (defect in NK cell cytotoxicity)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
Liver pathology
Pathology (EG):
Liver pathology
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
Similar liver injury and serum ALT levels
Refs:
Adachi et al., 2004, Int Immunol
Hyperlink: