Molecular group:
Immune cells
Molecule/Cell:
NK cells
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
400 sporozoites
Mouse genetic background (Con):
BALB/c
Experimental treatment group (EG):
anti-asialo GM1
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Earlier death (1-2 weeks); similar IFN-g protein in the liver 3 days p.i.
Refs:
Saeftel et al., 2004, Infect Immun
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