Molecular group:
Immune cells
Molecule/Cell:
B cells/gd T cells
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^5
Mouse genetic background (Con):
129/Sv x C57BL/6
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
m-MT x d -/- TCR
Lethal infection (Con):
no
Lethal infection (EG):
25%
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Developed a high persistent parasitemia (10-30%)
Additional phenotypes (EG vs Con):
N.I.
Refs:
Seixas et al., 1999, J Immunol
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