Molecular group:
Immune cells
Molecule/Cell:
CD8
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6J
Experimental treatment group (EG):
anti-CD8 (early treatment)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
No CM
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Prolonged survival (1-2 weeks)
Refs:
Yañez et al., 1996, J Immunol
Hyperlink: