Molecular group:
Immune cells
Molecule/Cell:
CD8+ T cell/CD1d-restricted NKT cells
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
Backcrossed for 11 generations
Experimental treatment group (EG):
b2 microglobuline -/-
Lethal infection (Con):
N.I.
Lethal infection (EG):
N.I.
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar on day 5
Additional phenotypes (EG vs Con):
Prolonged survival (days)
Refs:
Nie et al., 2009, PLoS Pathog
Hyperlink: