Molecular group:
Immune cells
Molecule/Cell:
CD8+ T cell/CD1d-restricted NKT cells
Plasmodium strain:
Plasmodium berghei K173
pRBC infection titer:
2 x 10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
b2 microglobuline -/-
Lethal infection (Con):
N.I.
Lethal infection (EG):
N.I.
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
Plasma IFN-g and splenic IFN-g mRNA expression 24h p.i. was abrogated
Refs:
Mitchell et al., 2005, Infect Immun
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