Molecular group:
Immune cells
Molecule/Cell:
MHC-II
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6 x 129
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
A -/- (↓MHC-II → ↓ CD4) + anti-NK1.1
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (91%)
Pathology (EG):
CM (100%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Yañez et al., 1996, J Immunol
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