MHC-II

Molecular group: 
Immune cells
Molecule/Cell: 
MHC-II
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
Backcrossed for 10 generations
Experimental treatment group (EG): 
IA-b -/- (↓MHC-II → ↓ CD4)
Lethal infection (Con): 
N.I.
Lethal infection (EG): 
N.I.
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Similar on day 5
Additional phenotypes (EG vs Con): 
Prolonged survival (days)
Refs: 
Nie et al., 2009, PLoS Pathog