CD4/CD8

Molecular group: 
Immune cells
Molecule/Cell: 
CD4/CD8
Plasmodium strain: 
Plasmodium chabaudi chabaudi AS
pRBC infection titer: 
5 x 10^3 trophozoites
Mouse genetic background (Con): 
C57BL/6
Experimental treatment group (EG): 
anti-CD4 and anti-CD8
Lethal infection (Con): 
no
Lethal infection (EG): 
no
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Increased peak and developed a high, persistent parasitemia
Additional phenotypes (EG vs Con): 
Similar parasite-specific IgM early during infection and no IgG
Refs: 
Süss et al., 1988, Infect Immun