CD4

Molecular group: 
Immune cells
Molecule/Cell: 
CD4
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
CBA/Ca, CBA/J
Experimental treatment group (EG): 
CD4+ T cells from mice with CM (LN derived)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (100%)
Pathology (EG): 
CM (100%)
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
More severe brain hemorrhages and earlier mortality when mice received CD4+ T cells from mice dying of CM than from normal mice
Refs: 
Grau et al., 1986, J Immunol