Molecular group:
Immune cells
Molecule/Cell:
CD4
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
anti-CD4 (early treatment)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (67%)
Pathology (EG):
No CM
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
No neurological symptoms; prolonged survival (~2 weeks)
Refs:
Yañez et al., 1999, Infect Immun
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