Molecular group:
Immune cells
Molecule/Cell:
CD4
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
anti-CD4 (early treatment)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
No CM
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
No neurological symptoms; prolonged survival
Refs:
Beghdadi et al., 2008, J Exp Med
Hyperlink: