Molecular group:
Immune cells
Molecule/Cell:
CD4
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6NCrlBR
Experimental treatment group (EG):
anti-CD4
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Increased peak and developed a high, persistent parasitemia
Additional phenotypes (EG vs Con):
High, persistent parasitemia coincided with the high level of reticulocytosis
Refs:
Podoba et al., 1991, Infect Immun
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