Molecular group:
Immune cells
Molecule/Cell:
ab T cell
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6J
Level of backcrossing:
N.I.
Experimental treatment group (EG):
b TCR -/- + adoptive transfer of a mixture of CD4+ and CD8+ T cells from WT or Nlrp3-/- mice
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM
Pathology (EG):
CM (33%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Reimer et al., 2010, Eur J Immunol
Hyperlink: