Molecular group:
Immune cells
Molecule/Cell:
T cells
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^5
Mouse genetic background (Con):
NIH
Experimental treatment group (EG):
Thymectomy + anti-CD4
Lethal infection (Con):
no
Lethal infection (EG):
75-100%
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Developed a high persistent parasitemia
Additional phenotypes (EG vs Con):
Serum NO3- low and similar to untreated and uninfected mice
Refs:
Taylor-Robinson et al., 1993, Science
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