Molecular group:
Immune cells
Molecule/Cell:
T cells
Plasmodium strain:
Plasmodium yoelii 17XNL
pRBC infection titer:
10^4
Mouse genetic background (Con):
BALB/c
Level of backcrossing:
N.I.
Experimental treatment group (EG):
Nude mice (nu/nu): no thymus thus no mature T cells
Lethal infection (Con):
no
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Increased without clearance
Additional phenotypes (EG vs Con):
N.I.
Refs:
Vinetz et al., 1990, J Immunol
Hyperlink: