Molecular group:
Immune cells
Molecule/Cell:
Lymphocytes
Plasmodium strain:
Plasmodium vinckei petteri CR
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6J x 129
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
JH-gene segment -/- (JHD -/-)
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
↑ gd T cells and similar numbers of CD4+ ab T cells in spleen
Refs:
Van der heyde et al., 1996, J Leukoc Biol
Hyperlink: