Molecular group:
Immune cells
Molecule/Cell:
Lymphocytes
Plasmodium strain:
Plasmodium berghei NK65
pRBC infection titer:
10^3 or 10^6 or 10^8
Mouse genetic background (Con):
SCID (C57BL/6 were used as controls)
Level of backcrossing:
N.I.
Experimental treatment group (EG):
no T/B cells
Lethal infection (Con):
yes
Lethal infection (EG):
N.I.
Pathology (Con):
Liver pathology
Pathology (EG):
No liverpathology
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
No liver injury; no cytotoxicity by hepatic NK cells against hepatocytes
Refs:
Adachi et al., 2004, Int Immunol
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