Molecular group:
Immune cells
Molecule/Cell:
Lymphocytes
Plasmodium strain:
Plasmodium chabaudi adami 556KA
pRBC infection titer:
10^6
Mouse genetic background (Con):
CB-17-SCID (genetically histocompatible with BALB/cHSD)
Level of backcrossing:
N.I.
Experimental treatment group (EG):
Adoptive transfer of immune T cells + anti-CD4
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Developed low levels of splenic CD4+ and gd T cells
Refs:
Van der Heyde et al., 1993, J Immunol
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