Molecular group:
Complement
Molecule/Cell:
C5aR
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
5 x 10^5
Mouse genetic background (Con):
B10.D2/nSnJ
Experimental treatment group (EG):
anti-C5aR
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
CM (25%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Patel et al., 2008, J Exp Med
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