Molecular group:
Complement
Molecule/Cell:
B/C2
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^5
Mouse genetic background (Con):
129/Sv
Level of backcrossing:
Pure strain (100%)
Experimental treatment group (EG):
H2-Bf/C2 -/-
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Slightly delayed and slightly increased peak
Additional phenotypes (EG vs Con):
↑serum IFN-g 6, 8 and 9 days p.i.
Refs:
Taylor et al., 2001, Infect Immun
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