Molecular group:
Metabolic markers
Molecule/Cell:
Catecholamines
Plasmodium strain:
Plasmodium berghei Pasteur
pRBC infection titer:
5 x 10^6
Mouse genetic background (Con):
Swiss -44
Experimental treatment group (EG):
phenoxybenzamine (alpha-adrenergic receptor antagonist)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Protects against pulmonary edema, although significance was not reached
Refs:
Cordeiro et al., 1984, Experiencia
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