Molecular group:
Metabolic markers
Molecule/Cell:
Apo-AI
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
129/Ola x C57BL/6J
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
Apo-AI -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (85%)
Pathology (EG):
CM (100%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
↓ plasma HDL cholesterol
Refs:
Combes et al., 2005, Am J Pathol
Hyperlink: