Molecular group:
Metabolic markers
Molecule/Cell:
NADPH oxidase
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
129/Sv x C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
gp91phox -/- (no ROS)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
CM (100%)
Parasitemia (EG vs Con):
Faster increase
Additional phenotypes (EG vs Con):
N.I.
Refs:
Sanni et al., 1999, J Infect Dis
Hyperlink: