Molecular group:
Metabolic markers
Molecule/Cell:
NOS2/B cells
Plasmodium strain:
Plasmodium chabaudi adami 556KA
pRBC infection titer:
10^6
Mouse genetic background (Con):
JHD (129 x C57BL/6)
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
NOS2 -/-
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
↓ serum NOx levels on day 10 and 20 p.i.
Refs:
Van der Heyde et al., 2000, J Immunol
Hyperlink: