Molecular group:
Neural or endothelial cell stress/damage/activation markers
Molecule/Cell:
HO-1
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^6
Mouse genetic background (Con):
DBA/2
Experimental treatment group (EG):
HO-1 expressing adenovirus in liver
Lethal infection (Con):
yes
Lethal infection (EG):
no
Pathology (Con):
Liver pathology and severe anemia
Pathology (EG):
No liverpathology
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
No ↑ in plasma AST and no liver portal and centrilobular vein necrosis
Refs:
Seixas et al., 2009, Proc Natl Acad Sci U S A
Hyperlink: