Molecular group:
Neural or endothelial cell stress/damage/activation markers
Molecule/Cell:
HO-1
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^6
Mouse genetic background (Con):
BALB/c-SCID
Level of backcrossing:
N.I.
Experimental treatment group (EG):
Hmox-1 -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
HP&A
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Earlier mortality (days)
Refs:
Seixas et al., 2009, Proc Natl Acad Sci U S A
Hyperlink: