Molecular group:
Neural or endothelial cell stress/damage/activation markers
Molecule/Cell:
COX-1/2
Plasmodium strain:
Plasmodium berghei K173
pRBC infection titer:
10^3
Mouse genetic background (Con):
C57BL/6J
Experimental treatment group (EG):
non-selective COX-1/2 inhibitor (indomethacin)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (58%)
Pathology (EG):
CM (62%)
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
N.I.
Refs:
Blok et al., 1992, J Infect Dis
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