Molecular group:
Angiogenic and coagulation factors
Molecule/Cell:
EPO
Plasmodium strain:
Plasmodium chabaudi AS
pRBC infection titer:
10^4
Mouse genetic background (Con):
A/J
Experimental treatment group (EG):
rmEpo
Lethal infection (Con):
yes (100%)
Lethal infection (EG):
yes (50%)
Pathology (Con):
SMA (100%)
Pathology (EG):
SMA (50%)
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Increased reticulocytosis; similar anemia; survived a challenge infection 5 weeks after primary infection
Refs:
Chang et al., 2004, J Infect Dis
Hyperlink: