Molecular group:
Angiogenic and coagulation factors
Molecule/Cell:
EPO
Plasmodium strain:
Plasmodium chabaudi AS
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
anti-hEpo
Lethal infection (Con):
no
Lethal infection (EG):
yes (~70%)
Pathology (Con):
N.I.
Pathology (EG):
SMA (~70%)
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Prolonged severe anemia; delayed induction of reticulocytosis
Refs:
Chang et al., 2004, J Infect Dis
Hyperlink: