PAFR

Molecular group: 
Angiogenic and coagulation factors
Molecule/Cell: 
PAFR
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6
Experimental treatment group (EG): 
PAFR selective antagonist (UK74,505)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (100%)
Pathology (EG): 
CM (40-75%)
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Recovered from weight loss at the time point when WT mice succumbed
Refs: 
Lacerda-Queiroz et al., 2012, Am J Pathol