Molecular group:
Angiogenic and coagulation factors
Molecule/Cell:
Tissue PA (tPA)
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6 x 129/Sv
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
tPA -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM
Pathology (EG):
CM
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Piguet et al., 2000, Infect Immun
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