Fas

Molecular group: 
Leucocyte effector mechanisms and proteases
Molecule/Cell: 
Fas
Plasmodium strain: 
Plasmodium berghei NK65
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
Fas -/- (lpr)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
Liver pathology
Pathology (EG): 
Liver pathology
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
Similar serum GPT (ALT), liver injury and lymphocyte infiltration in liver
Refs: 
Adachi et al., 2001, J Immunol