Molecular group:
Leucocyte effector mechanisms and proteases
Molecule/Cell:
Fas
Plasmodium strain:
Plasmodium yoelii 17XNL
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
Fas -/- (lpr)
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
None
Pathology (EG):
None
Parasitemia (EG vs Con):
Increased peak and delayed clearance
Additional phenotypes (EG vs Con):
N.I.
Refs:
Ohno et al., 2005, Immunogenetics
Hyperlink: