Molecular group:
Leucocyte effector mechanisms and proteases
Molecule/Cell:
Fas
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
CBA/N
Level of backcrossing:
N.I.
Experimental treatment group (EG):
Fas -/- (lpr)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM
Pathology (EG):
CM (50%)
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Heterozygotes not different from WT
Refs:
Ohno et al., 2005, Immunogenetics
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