Fas

Molecular group: 
Leucocyte effector mechanisms and proteases
Molecule/Cell: 
Fas
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
Fas -/- (lpr)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM
Pathology (EG): 
CM (50%)
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Heterozygotes not different from WT
Refs: 
Ohno et al., 2005, Immunogenetics