Fas

Molecular group: 
Leucocyte effector mechanisms and proteases
Molecule/Cell: 
Fas
Plasmodium strain: 
Plasmodium berghei K173
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6 for WT, N.I. for Lpr
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
Fas -/- (lpr)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
HP&A
Pathology (EG): 
HP&A
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Similar hematocrit and splenomegaly, no cerebral pathology (similar to WT mice)
Refs: 
Potter et al., 2006, J Neuroimmunol