Molecular group:
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell:
FcgRI
Plasmodium strain:
Plasmodium berghei tg for P. falciparum MSP19
pRBC infection titer:
5 x 10^3
Mouse genetic background (Con):
Tg BALB/c x BALB/c F1
Experimental treatment group (EG):
Hu-FcRI-tg + anti-PfMSP-1
Lethal infection (Con):
yes
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Decreased (undetectable)
Additional phenotypes (EG vs Con):
N.I.
Refs:
McIntosh et al., 2007, PLoS Pathog
Hyperlink: