PD-L1/LAG-3

Molecular group: 
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell: 
PD-L1/LAG-3
Plasmodium strain: 
Plasmodium chabaudi
pRBC infection titer: 
10^5
Mouse genetic background (Con): 
C57BL/6
Experimental treatment group (EG): 
anti-PD-L1 + anti-LAG-3
Lethal infection (Con): 
no
Lethal infection (EG): 
no
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Similar peak and no recrudescences (complete parasite elimination)
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Butler et al., 2012, Nat Immunol