Molecular group:
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell:
PD-L1/LAG-3
Plasmodium strain:
Plasmodium chabaudi
pRBC infection titer:
10^5
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
anti-PD-L1 + anti-LAG-3
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar peak and no recrudescences (complete parasite elimination)
Additional phenotypes (EG vs Con):
N.I.
Refs:
Butler et al., 2012, Nat Immunol
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