Molecular group:
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell:
PD-L1/LAG-3
Plasmodium strain:
Plasmodium yoelii 17XNL
pRBC infection titer:
10^5
Mouse genetic background (Con):
Swiss Webster
Experimental treatment group (EG):
anti-PD-L1 + anti-LAG-3
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Decreased
Additional phenotypes (EG vs Con):
N.I.
Refs:
Butler et al., 2012, Nat Immunol
Hyperlink: