CTLA-4/TNF

Molecular group: 
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell: 
CTLA-4/TNF
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^4
Mouse genetic background (Con): 
BALB/cAnNCrl
Experimental treatment group (EG): 
anti-CTLA-4 + anti-TNF
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (~30%)
Pathology (EG): 
CM (~80%)
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Hafalla et al., 2012, PLoS Pathog