Molecular group:
Signal transduction and intracellular danger sensors
Molecule/Cell:
TRIF
Plasmodium strain:
Plasmodium yoelii 17XNL
pRBC infection titer:
5 x 10^6
Mouse genetic background (Con):
N.I.
Level of backcrossing:
N.I.
Experimental treatment group (EG):
TRIF -/-
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Similar serum IL-12p40 6 days p.i.
Refs:
Cramer et al., 2008, Microbes Infect
Hyperlink: