Molecular group:
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell:
TLR9/IFN-g
Plasmodium strain:
Plasmodium yoelii 17XL
pRBC infection titer:
1 - 1,5 x 10^4
Mouse genetic background (Con):
TLR9 -/- (C57BL/6)
Level of backcrossing:
Backcrossed for at least 15 generations
Experimental treatment group (EG):
anti-IFN-g
Lethal infection (Con):
50%
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
N.I.
Refs:
Hisaeda et al., 2008, J Immunol
Hyperlink: