TLR6

Molecular group: 
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell: 
TLR6
Plasmodium strain: 
Plasmodium berghei NK65
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
129/Sv x C57BL/6
Level of backcrossing: 
Backcrossed for 2 generations
Experimental treatment group (EG): 
TLR6 -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
Liver pathology
Pathology (EG): 
Liver pathology
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Similar serum IL-12 and liver injury
Refs: 
Adachi et al., 2001, J Immunol