Molecular group:
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell:
Class A type I and II macrophage scavenger receptors
Plasmodium strain:
Plasmodium chabaudi AS
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
SR-AI/II -/-
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Similar phagocytosis of pRBCs and free merozoites by peritoneal macrophages
Refs:
Su et al., 2002, J Infect Dis
Hyperlink: