Molecular group:
Adhesion molecules
Molecule/Cell:
CD54 (ICAM-1)
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
CBA/Ca
Experimental treatment group (EG):
soluble ICAM-1
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
CM (100%)
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Prolonged survival (days)
Refs:
Grau et al., 1991, Eur J Immunol
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